Glucagon and Aging - Breakfast How Not To Start The Day Part III

A question from one of our readers:

Dr. Mericle,

With respect to burning "fat" energy in the mornings before eating, what if you are not a long distance runner? The average person is not, particularly someone who is overweight. A typical run for me in my current condition is 2-3 miles. Would I still be burning fat with a 25-30 min. jog?

JoLee

Answer: Yes, you would still be burning fat as long as you stay in a glucagon state.

This is a very good question since most people today don't run at all -much less even 2-3 miles a day. This touches on one of the most important aspects of the MericleDiet and exercise as it relates to weight loss. Exercise for your immune system, but don't rely on exercise to lose weight and or keep weight off. Even running seven miles a day is not enough to burn any significant calories.

Back to the glucagon state of energy utilization

In the last newsletter I discussed the importance of entering a glucagon state for some part of every day. For me, running helps as it is a real distraction, something I do every day and I have my own rule of never eating before I run. The reason for not eating is that it is a lot easier to run in a state of energy utilization (glucagon) , not energy storage (insulin). Usually in hot weather I will run first thing in the morning. This actually shortens my glucagon phase as compared to running in the late afternoon. Usually if it is hot and I run early, I will try not to eat when I get back from the run until noon at the earliest. This gives me at least four or five hours in a glucagon state -higher energy levels and I get a lot more done. If you are going to eat early in the day, it is best to eat low on the glycemic index. Organic fruit, carrot or celery sticks and fresh organic salads are good choices.

You don't need to exercise to enter a glucagon state

Exercise can help to get you into a glucagon phase but is not necessary. All you really have to do is not go into an insulin state by eating. Most of us are going to eat something during most days but it is optimal if you can limit the time of food ingestion to the mid-day hours, noon to 6:pm or so. You will have a good glucagon phase in the morning and not go to bed on a large load of insulin in the evening. As mentioned previously, hyperinsulinism is implicated in many of our serious lifestyle illnesses.

Dr. Roy Walford and caloric restriction

It may seem hard to believe, but during periods of starvation during WWII, those who had their caloric intake reduced, had improvement in diseases such as heart disease and cancer. It was also noted that they did not age as much. This has been studied by the late Dr. Roy Walford, who was part of the Biosphere. There is no question that calorically restricted mice age much more slowly than those who are allowed to eat what they want. Dr. Walford also made the point that the calories that are eaten must be "nutritionally dense." This is also one of the premises of the MericleDiet. I don't want to suggest that one live a life of caloric restriction, but there is no doubt that reducing your caloric intake and not eating as often or as much will improve your health and slow your aging.

Insulin Glucagon Aging

Somewhere in the basic premise of caloric restriction and retarded aging is the yin and yang of human energy management -Glucagon and Insulin. Too much of either is not good and as noted previously, most people in America have way too much insulin. If you want to feel better and look better while you age more slowly, think glucagon, not insulin. Try to achieve "balance" between them. If you spend four hours a day in an insulin state, try to spend at least as much time in a glucagon state.

Conclusion

Understanding how glucagon and insulin affect your health and your weight is one of the most important concepts one can learn. Not only will you be able to work better, feel better and control your weight more easily, there now is impressive evidence that restricting your insulin secretion by reducing your frequency and quantity of feedings will retard aging.

Reference:

Dr. Walford and Caloric Restriction
http://www.walford.com
Stryer Biochemistry Fourth Edition
Thanks for your time.

Copyright ? John Mericle M.D. All Rights Reserved

For more information on the MericleDiet or to signup for Dr. Mericle's Newsletter click on the link below.

http://www.walford.com

tidy up service Northbrook ..
In The News:

ETA sharing on Apple Maps and Google Maps keeps contacts updated automatically while you drive safely. Learn step-by-step instructions for iPhone and Android.
Data removal from brokers protects against AI-powered scams and deepfake threats in 2026. Learn how data brokers sell your personal information to scammers.
Learn how to act against cybercriminals in 2026 with essential security steps like two-factor authentication, software updates and credit freezing.
Choose between OpenAI releasing Sora text-to-video model, the AI race heating up, or Waymo driverless cars launching in cities across the country
Learn how to set up Google Maps and Apple Maps on your phone to automatically remember where you parked. Step-by-step instructions for enabling location services and parking detection.
Phishing scammers use rnicrosoft.com domain to impersonate Microsoft by replacing "m" with "rn" in typosquatting attacks that steal login credentials.
OpenAI announces new teen safety rules for ChatGPT users under 18, blocking romantic roleplay and requiring extra caution on body image topics.
A 2025 data breach at fintech company 700Credit exposes personal information of more than 5.8 million people through compromised third-party integration partner.
Retailers lose $76.5 billion annually to return fraud as nearly 10% of U.S. retail returns involve fraudulent activity, with $850 billion in returns expected in 2025.
ShinyHunters claims responsibility for stealing 94GB of Pornhub user data affecting over 200 million records and demands Bitcoin ransom.
ChatGPT 2025 now connects to Apple Music, Canva, Expedia, TripAdvisor and OpenTable through built-in apps that help users create playlists, design graphics and more.
Apple releases emergency patches for two zero-day vulnerabilities actively exploited in attacks. iPhone and iPad users urged to update immediately.
DoorDash launches Zesty, an AI-powered social app that recommends restaurants through conversational search, now testing in San Francisco and New York.
Cybersecurity firm Infoblox reveals that over 90 percent of parked domains now redirect visitors to scams and malware, making simple typos extremely dangerous.
The Fox News AI Newsletter covers the latest artificial intelligence technology advancements, including the challenges and opportunities AI presents now and for the future.
GPT-5.2 is now live for all ChatGPT users with improved coding, writing and image interpretation, with Kurt Knutsson offering his review.
New iPhone replacement scam uses pressure tactics and fake carrier calls to steal devices from buyers. Criminals claim shipping errors and demand urgent returns.
Amazon Ring's new facial recognition feature sparks privacy controversy as Electronic Frontier Foundation critics argue the AI upgrade expands surveillance risks.
New Android banking trojan Sturnus steals credentials, reads encrypted messages and controls devices.
Denmark's 3D-printed student village proves automation builds 36 apartments faster than traditional methods. Skovsporet project shows housing future.
Discover Android's new Sound Notifications feature that alerts you to smoke alarms, doorbells, and baby cries even when wearing headphones.
New SantaStealer malware reportedly threatens holiday shoppers with password theft. This Christmas-themed info-stealer targets browsers and crypto wallets.
The Christmas season brings a surge in Netflix phishing scams targeting shoppers with fake emails. Stacey P received convincing scam but verified account first.
San Francisco Giants invite Jamie Grohsong to throw ceremonial first pitch at Oracle Park after he learned to play baseball with a bionic hand following an injury.
FBI warns cybercriminals are stealing family photos from social media to create fake proof of life images in virtual kidnapping scams targeting victims.

Weight Loss: Goal-Setting for Success

If you were going to travel to the other side... Read More

How the Protein Diet Works

Protein is an essential nutrient necessary for maintaining good health.... Read More

Fast Weight Loss Secret Revealed ? Move it or Lose it!

Some of you will not like what I have to... Read More

Fat Burners: The Shocking Truth

Fat Burners refer to the hundreds of products on the... Read More

How to Lose Belly Fat: Latest Secrets from the Research Labs, Part 1

In this series of articles, you will learn exactly how... Read More

Dieting? Want and Desire are Dangerous

This is a very important topic that needs to be... Read More

The Truth About Dieting And Weight Loss

You may not like what I'm about to say, but... Read More

Walking for Weight Loss: Walking with a Purpose

I wrote this article back in the late fall when... Read More

Myth: Gastric Bypass Patients Can Never Be Nutritionally Healthy

A common claim from gastric bypass detractors is that after... Read More

Close Kept Secrets to Weight Loss Lesson #7

Well, look at you go! You keep moving closer and... Read More

Resolve + Enthusiasm = Power

Think for a moment about the highest mountain you ever... Read More

Fat Lady in a Thin Body: WLS Patients Feel Like Imposters

Every weight loss surgery patient I've met said they at... Read More

No Fuss Weight-Loss

To lose weight and keep it off you need an... Read More

The Importance and Confusion of Fat in Your Diet

Fats are always looked at as a negative in a... Read More

Dropping The Carbs - The Pros and Cons of Ketogenic Dieting

We must all now be familiar with the Atkins Diet.... Read More

Weight Loss: Weight Loss is All in Your Mind!

"The kind of thoughts that you plant in your mind,... Read More

Walking, Water, and Weight Watchers: The 3 W?s for Weight Loss

I have been seriously working on losing weight for about... Read More

Secrets Of Weight Loss

One thing's for sure, in this day & age, if... Read More

Slimming Solutions

Here are 5 solutions to slimming:1. Set Mini-Goals: Try setting... Read More

Pathological Eating Disorders and Poly-Behavioral Addiction

When considering that pathological eating disorders and their related diseases... Read More

Why Are There Different Diet Types?

Diet is a dreadful word for most of us because... Read More

Walking: A Key to Weight Loss

Doctors prescribe Walking as the best medicine for weight loss.We... Read More

Quick Weight Loss Secrets

The Secrets have been in our family recipes, some even... Read More

Overweight - Answering Your Critics

There are those that walk amongst us who have followed... Read More

Weight Loss: N Y Millionaire Weight Loss ?Secret? Revealed

It is a fact that about 70% Americans are overweight.... Read More

reliable home cleaners Buffalo Grove ..