Supporters of the Atkins Diet claim that a low carbohydrate diet is a safe and effective method for losing weight. This article evaluates the low carbohydrate diet and specifically the claims made about ketosis.
The Low Carb-Ketosis Link
By severely limiting carbohydrates in your diet, the main energy source used by your body, glucose, drops to low levels. In return, insulin levels also drop. With low glucose and low insulin levels, the body turns to alternative sources of energy.
Because of a significant change in your body's chemistry when on the Atkins Diet, certain metabolic pathways are turned "on" that are normally not "on" or run at very low levels. One such pathway involves the breakdown of fat, called Beta-Oxidation of Fats.
Now, normally fats are broken down to produce energy when your body senses a need. But in the context of a low Carb diet, the normal breakdown pathway of fats is altered and an alternative pathway kicks in. This alternative pathway produces what are called ketone bodies.
Ketosis is the term used to describe when ketone bodies are circulating in your bloodstream. The ketone bodies can be used as alternative sources of energy by, most importantly, your brain.
In case you might be curious, the three ketone bodies produced by this alternative pathway for breaking down fat are acetoacetate, beta-hydroxybutyrate, and acetone. These ketone bodies are formed in your liver and then are transported to other tissues, mainly the brain. In your brain, they are converted back to a form that can provide direct energy during times of starvation.
Here is the whole process...
So, the Atkins Diet (and any low Carb diet) produces a low energy state (low glucose) that causes the breakdown fat using an alternative pathway that leads to the development of ketosis.
So far it sounds pretty good. By limiting Carbs in your diet, you can essentially force your body into breaking down stored fat, the very thing you need to get rid of to lose weight.
But there are problems...
Atkins Diet and Toxicity
Ketone bodies are toxic. Many supporters of low Carb diets claim that ketosis is safe. They state that they are natural byproducts of fat breakdown and even babies have high levels of circulating ketone bodies.
First, they are not natural by-products of fat metabolism. The normal beta-oxidation of fats does produce ketone bodies but these are incorporated into the normal cycle of energy production, called the Krebs cycle. When ketone bodies are circulating in your bloodstream, it signals an abnormal physiologic state, called starvation. They are not incorporated into the normal energy cycle, the Krebs cycle, and spill into the bloodstream.
Just because your body has the ability to transport ketone bodies to certain tissues and then use them for energy, does not make it a normal process. It is an alternative pathway that turns "on" only when your body is faced with depleted levels of the main energy source, glucose.
Secondly, babies are not small adults. A baby's liver and brain tissue are made up of different chemicals and pathways, specifically geared to handle the high fat diet coming from mother's milk. These pathways change as a baby grows and starts to eat other foods. Eventually, the normal adult pathways are set up and the infantile chemistry used as evidence to support the safety of ketosis, stop working.
But this is not even related to the fact that ketone bodies are toxic. In medicine, the three ketone bodies mentioned above are classified as toxic acidic chemicals. At high levels, they can cause your blood to become too acidic, a disease state called ketoacidosis.
Granted, this is rare because most of the ketone bodies will be used by the brain as an energy source. Ketoacidosis is usually seen in type 1 diabetics. It is a medical emergency.
So, is ketosis dangerous to your body? Yes and no. Yes, ketosis represents a state of starvation. Losing weight when the body thinks you're starving is the best way to guarantee weight regain. The weight will come back and come back as fat. No, ketosis will not cause ketoacidosis in non-diabetics. And as long as you have a large storage of fat, your brain will not starve for energy.
The Final Verdict
However, it is well known that microscopic damage can occur to the kidneys effecting their ability to filter the blood. But clinical signs of this damage may take several years to manifest. Chronic renal insufficiency is a concern for ketogenic dieters, which may cause problems in the years to come.
Conclusion
Atkins Diet and other ketogenic diets (low Carb) can be safe and effective in causing weight loss. However, I recommend keeping ketosis to a minimum and keep your carbohydrate intake above 50 grams a day. Don't follow the suggestions for reaching an "induction" phase. It's not necessary to turn "on" the alternative pathways described above and burn fat.
Remember, healthy weight loss is to burn fat and fat only. But it also involves keeping your rate of weight loss around 2-3 pounds/week. The induction phase promoted by the Atkins Diet can result in a rate of weight loss far greater than 2-3 pounds/week. It may sound good to you now, but how does gaining it all back as fat sound? Because that will happen if you lose weight too fast.
For more information on ways to experience healthy weight loss, visit
To Healthy Living!
Dr. Michael A. Smith
Chief Medical Consultant
Diet Basics Website
Dr. Smith is the Chief Medical Consultant to Diet Basics, a content rich weight loss site dedicated to all dieters fighting to lose weight. Please visit his site at...diet basics
One visit and you'll be convinced that Dr. Smith and Diet Basics is your on-line resource for healthy weight loss!
You gain weight when your calorie intake is more than... Read More
Weight loss programs often have big claims. Understand the "science"... Read More
Just because you're working hard, doesn't mean that you're working... Read More
You are ready to shed those energy draining, body crippling,... Read More
So many people are talking about how slow their metabolism... Read More
A question from one of our readers:Dr. Mericle,With respect to... Read More
Most Americans do not get enough calcium in their diets;... Read More
Have you ever experienced this scenario before?"I have successfully lost... Read More
FACT: Obesity accounts for 300,000 deaths a year in the... Read More
If you are fighting the battle of the bulge (overweight... Read More
One thing's for sure, in this day & age, if... Read More
There are many factors that cause us to increase body... Read More
The main reasons most people have difficulty maintaining their ideal... Read More
You won't believe what happened to me today!I was getting... Read More
Control that sweet tooth. Remember that sweet things generally mean... Read More
All of the things we tell sick people so that... Read More
With obesity and disease increasing dramatically, many fitness experts are... Read More
Steady gains made in improvement in life expectancy may be... Read More
You know you have will-power. You can change a diaper... Read More
I've worked with hundreds of people who were interested in... Read More
Healthy living begins with healthy eating and healthy eating begins... Read More
It's a sad comment on human nature that prejudice and... Read More
Weight Watchers inspired me to change my eating habits, lose... Read More
If you are about to begin a diet, the number... Read More
Eighteen or twenty years ago, I was into high protein,... Read More
kitchen deep cleaning Glenview ...The rediscovery of the wealth of the wonder drug Hoodia... Read More
When you begin the decision making process to have Weight... Read More
Are you a hopeless carbohydrate addict? Let's conquer these cravings... Read More
Diet information is everywhere. In advertisements, on TV, in magazines;... Read More
False campaignsMore than 50 percent of Americans and Canadians are... Read More
Everyone has their own individual reason for joining a health... Read More
If you've been working out with weights for any length... Read More
The first rule for successful weight loss and weight maintenance... Read More
For a healthy body, it is very important to have... Read More
Breaking Down Cravings One at a TimeI know you've heard... Read More
With all of the conflicting studies and fuzzy interpretation of... Read More
Obesity and fast foods - there's little doubt about the... Read More
Glycemic index ranks different carbohydrate foods depending on their potential... Read More
Include in your diet things that contain more water like... Read More
Gastric Bypass surgery is becoming increasingly more popular for the... Read More
Atkins Nutritionals filed for bankruptcy at the beginning of August... Read More
Healthy living begins with healthy eating and healthy eating begins... Read More
We in the diet and exercise industry have our own... Read More
Fat burning exercise is not merely one that will burn... Read More
How's this for a diet: Take in fewer calories than... Read More
Weight loss from exercise can be achieved by walking, running,... Read More
When you're taking Phentermine, you should go to the emergency... Read More
Are you unhappy with your current weight but aren't "motivated"... Read More
It seems everyone is looking for that magic bullet -... Read More
Generally, weight loss surgery such as the gastric bypass will... Read More
Weight Loss |