Supporters of the Atkins Diet claim that a low carbohydrate diet is a safe and effective method for losing weight. This article evaluates the low carbohydrate diet and specifically the claims made about ketosis.
The Low Carb-Ketosis Link
By severely limiting carbohydrates in your diet, the main energy source used by your body, glucose, drops to low levels. In return, insulin levels also drop. With low glucose and low insulin levels, the body turns to alternative sources of energy.
Because of a significant change in your body's chemistry when on the Atkins Diet, certain metabolic pathways are turned "on" that are normally not "on" or run at very low levels. One such pathway involves the breakdown of fat, called Beta-Oxidation of Fats.
Now, normally fats are broken down to produce energy when your body senses a need. But in the context of a low Carb diet, the normal breakdown pathway of fats is altered and an alternative pathway kicks in. This alternative pathway produces what are called ketone bodies.
Ketosis is the term used to describe when ketone bodies are circulating in your bloodstream. The ketone bodies can be used as alternative sources of energy by, most importantly, your brain.
In case you might be curious, the three ketone bodies produced by this alternative pathway for breaking down fat are acetoacetate, beta-hydroxybutyrate, and acetone. These ketone bodies are formed in your liver and then are transported to other tissues, mainly the brain. In your brain, they are converted back to a form that can provide direct energy during times of starvation.
Here is the whole process...
So, the Atkins Diet (and any low Carb diet) produces a low energy state (low glucose) that causes the breakdown fat using an alternative pathway that leads to the development of ketosis.
So far it sounds pretty good. By limiting Carbs in your diet, you can essentially force your body into breaking down stored fat, the very thing you need to get rid of to lose weight.
But there are problems...
Atkins Diet and Toxicity
Ketone bodies are toxic. Many supporters of low Carb diets claim that ketosis is safe. They state that they are natural byproducts of fat breakdown and even babies have high levels of circulating ketone bodies.
First, they are not natural by-products of fat metabolism. The normal beta-oxidation of fats does produce ketone bodies but these are incorporated into the normal cycle of energy production, called the Krebs cycle. When ketone bodies are circulating in your bloodstream, it signals an abnormal physiologic state, called starvation. They are not incorporated into the normal energy cycle, the Krebs cycle, and spill into the bloodstream.
Just because your body has the ability to transport ketone bodies to certain tissues and then use them for energy, does not make it a normal process. It is an alternative pathway that turns "on" only when your body is faced with depleted levels of the main energy source, glucose.
Secondly, babies are not small adults. A baby's liver and brain tissue are made up of different chemicals and pathways, specifically geared to handle the high fat diet coming from mother's milk. These pathways change as a baby grows and starts to eat other foods. Eventually, the normal adult pathways are set up and the infantile chemistry used as evidence to support the safety of ketosis, stop working.
But this is not even related to the fact that ketone bodies are toxic. In medicine, the three ketone bodies mentioned above are classified as toxic acidic chemicals. At high levels, they can cause your blood to become too acidic, a disease state called ketoacidosis.
Granted, this is rare because most of the ketone bodies will be used by the brain as an energy source. Ketoacidosis is usually seen in type 1 diabetics. It is a medical emergency.
So, is ketosis dangerous to your body? Yes and no. Yes, ketosis represents a state of starvation. Losing weight when the body thinks you're starving is the best way to guarantee weight regain. The weight will come back and come back as fat. No, ketosis will not cause ketoacidosis in non-diabetics. And as long as you have a large storage of fat, your brain will not starve for energy.
The Final Verdict
However, it is well known that microscopic damage can occur to the kidneys effecting their ability to filter the blood. But clinical signs of this damage may take several years to manifest. Chronic renal insufficiency is a concern for ketogenic dieters, which may cause problems in the years to come.
Conclusion
Atkins Diet and other ketogenic diets (low Carb) can be safe and effective in causing weight loss. However, I recommend keeping ketosis to a minimum and keep your carbohydrate intake above 50 grams a day. Don't follow the suggestions for reaching an "induction" phase. It's not necessary to turn "on" the alternative pathways described above and burn fat.
Remember, healthy weight loss is to burn fat and fat only. But it also involves keeping your rate of weight loss around 2-3 pounds/week. The induction phase promoted by the Atkins Diet can result in a rate of weight loss far greater than 2-3 pounds/week. It may sound good to you now, but how does gaining it all back as fat sound? Because that will happen if you lose weight too fast.
For more information on ways to experience healthy weight loss, visit
To Healthy Living!
Dr. Michael A. Smith
Chief Medical Consultant
Diet Basics Website
Dr. Smith is the Chief Medical Consultant to Diet Basics, a content rich weight loss site dedicated to all dieters fighting to lose weight. Please visit his site at...diet basics
One visit and you'll be convinced that Dr. Smith and Diet Basics is your on-line resource for healthy weight loss!
You've heard the popular advice on weight loss diets. Cut... Read More
Are you one of the 90 million Americans who are... Read More
So you're overweight, "fat"--to be honest--and you want to start... Read More
Is it easy to lose weight? Yes. Losing weight is... Read More
Getting enough of the good fats will help you lose... Read More
A number of popular diets are focused on carbohydrates. Some... Read More
Dieting and weight loss is almost certainly the most lucrative... Read More
"Hey, you have reduced now, compared to the last time... Read More
After patients have had gastric bypass surgery comes a very... Read More
No doubt about it, when we feel stressed we want... Read More
Welcome to lesson #2. First of all, I believe that... Read More
Dieting is not easy. If it were, we would probably... Read More
Ok... If you are reading this is because you do... Read More
Quick weight loss is promised by diets all the time.... Read More
Yep, it is that time of year again! Time to... Read More
In a culture of blame-shifting we often look for someone... Read More
Have you ever experienced this scenario before?"I have successfully lost... Read More
1. What is Atkins Diet? Dr. Atkins diet, first introduced... Read More
Over the past 5 years, online weight loss programs have... Read More
There are several factors in winning at weight loss. Sometimes... Read More
We all know it's hard to begin losing weight, no... Read More
WHAT DOES BEING FIT REALLY MEAN?The "INSIDE-OUT" approach to fitness... Read More
Drink plenty of water. Our body needs a lot of... Read More
The cost of a tummy tuck is something to consider... Read More
Browsing one of the Russian websites I have recently found... Read More
same day cleaning service Glencoe ...There are tons of fad diets and weight loss schemes... Read More
Are you Telling Yourself It's Too Hard to Lose Weight?Telling... Read More
* Not walking on a treadmill everyday for 45 minutes... Read More
I want to make this perfectly clear, fruits are healthy... Read More
There are lots of dieters, trying every sort of plan... Read More
CancerCoronary heart diseaseStrokeOsteoporosisMajor Depression from Brain StarvationHeadlines.WASHINGTON, Jun 22, 2004... Read More
When it all comes down to losing or gaining weight,... Read More
When we hear all the success stories of the gastric... Read More
Finally - you are alone. No one else is around.... Read More
Browsing one of the Russian websites I have recently found... Read More
Teenagers with body mass indices between 25 and 30 require... Read More
Are you overweight?Most people are afraid to admit they are.It... Read More
Any weight loss or diet plan, including low-carb plans like... Read More
We must all now be familiar with the Atkins Diet.... Read More
Both men and women around the world are becoming fatter... Read More
If you have been eating as usual and the pounds... Read More
Exercise Physiologists who study the effects of exercise on weight... Read More
With the number of people suffering from obesity rising so... Read More
The Quest to Reach Your Ideal WeightIt was late in... Read More
On the market at any given time, there are hundreds... Read More
Weight loss is a hot topic among college students today,... Read More
Weight Loss Surgery (WLS) is often viewed as a quick... Read More
It has been 15 years since I was diagnosed with... Read More
Dieting presents many complications if you are not fully committed... Read More
"The sovereign invigorator of the body is exercise, and of... Read More
Weight Loss |