backyard room additions easy house additions home addition with basement third lake home addition construction buffalo grove md kitchen and bath buffalo grove .. Chicago Drug testing

What Obesity Debate?

This is a perfect example of how on-line weight loss "experts" can confuse and harm the American consumer...The Obesity Debate?

During a dinner conversation with a friend, the topic of laziness was brought up. From there, we some how got around to the topic of obesity. He said to me, "A great example of how bad laziness can be is obesity."

"Excuse me," I coughed out (almost chocking on the last bite).

"You know, obese people don't do anything. They are fat because they are lazy," my friend said as if from a position of authority. This was going to be a long dinner I could tell.

It turns out, my friend read an article posted on the net that started with a statement similar to my friend's words that almost made me choke. Unfortunately, he didn't remember the author's name but the title was Fitness and Exercise -- I haven't found it...yet.

What blows my mind is how easily people believe what is written on a website by someone calling himself an expert! The real experts need to start making noise!

Laziness does not cause obesity. If that were so, obesity would be the norm and not considered a problem. I recently found a wonderful definition of covers all the possibilities in one clear sentence:

The etiology of obesity is complex, determined by the interplay of genetic and environmental factors -Andrea Baessler, from her recent article in Diabetes, Jan, 2005.

There has never been a debate about what causes obesity. We have always known that obesity is multifactorial in etiology. The "real" debate topics are which environmental factors and which genes increase the risk or incidence of obesity. The rest of the article reviews recent work around two genetic links to obesity.

SREB-1 Gene

Delphine Eberle's work (Diabetes, Aug, 2004), with the sterol regulatory element binding protein transcription factor, found that the two isoforms are linked to the "plasma leptin concentrations in American obese families."

His group hypothesized, "...genetic variations of the SREB-1 gene could be associated with obesity and obesity-related metabolic traits such as insulin resistance, type 2 diabetes, and dyslipidemia."

Interestingly, SREB-1 gene polymorphisms were found among obese cohorts when compared to nonobese cohorts. This means they are on to something and possibly not far from marking the SREB-1 gene as a clear link to obesity (1).

Ghrelin Receptor Gene (GHSR)

The importance of ghrelin in the central regulation of feeding has been demonstrated in animals and humans. Ghrelin increases appetite and food intake in normal subjects and patients with decreased appetite, such as those suffering from cancer cachexia. Recent evidence suggests that obesity is associated with an impairment of the entire ghrelin system (2).

Besides its biological function, the ghrelin receptor gene is located in a quantitative trait locus or QTL strongly linked to six phenotypes of obesity (1).

This is a second strong genetic association to obesity. Both groups will soon have conclusive evidence to support their arguments for SREB-1 and GHSR genetic links to obesity.

As far as I can tell, laziness wasn't mentioned once. How many wonderful people avoid treatment because they actually believe it's their own fault?

Educate at all costs.

Healthy Living!
Michael A. Smith, M.D.

Additional Information is available at The Weight Loss Professional


  • Baessler A, Hasinoff J, Fischer M: Genetic linkage and association of the growth hormone secretagogue receptor gene in human obesity. Diabetes, Jan, 2005.

  • Eberle D. SREB-1 gene polymorphisms are associated with obesity and type 2 diabetes in French obese and diabetic cohorts. Diabetes, Aug, 2004.

  • Flegal KM, Carroll MD, Ogden CL, Johnson CL: Prevalence and trends in obesity among US adults, 1999-2000. JAMA 288:1723-1727, 2002
  • Dr. Smith is the primary physician and consultant for the Weight Loss Professional Website. His interests include preventative medicine, the genetic etiology of obesity, and several others too numerous to list.

    Please visit his website at and let him know what you think.

    In The News:

    Health Secrets of Cayenne

    For many years, herbalists believe that Cayenne is the most... Read More

    Are You Confused By All The Different Diets? Heres A Quick Diet Comparison

    It would not be surprising to hear your answer is... Read More

    Read Food Labels To Lose Weight

    I was at the grocery store the other day, doing... Read More

    Are Weight Loss Supplements Right For You?

    The debate about whether supplements for weight loss are healthy... Read More

    Fourteen Reasons Why Dieting Is Bad For Your Health

    1. The lower the calories eaten per day, the harder... Read More

    Eating Food Just to Be Rid of It

    What to Do with the Leftovers?Okay, tell me if you've... Read More

    Calorie Burn? Know The Optimum Walking Speed For Greatest Results

    Calorie burn can be really enhanced if you follow a... Read More

    3 Easy Dieting Success Tips

    1. Drink 8-10 glasses of water each dayOkay, for many... Read More

    Weight Loss & Obesity Affects Life Expectancy

    We hear it all the time?lose weight for your health.... Read More

    Why Do You Say You Want To Lose Weight?

    How many of your New Year's resolution start out with... Read More

    Weight Loss With Bontril: Smooth Sailing On The Weight Loss Ocean

    As many of us know, it's the first few days... Read More

    7 Diet Tips For Rapid Weight Loss

    1. Quit snacking in between meals. Do not fall for... Read More

    Hoodia - An Elixir that Fights Obesity Part 1

    Humanity is always in search of a wonder drug that... Read More

    How To Get Slim With Healthy Eating Habits

    Many women want to be slim. Maybe you're one of... Read More

    How Can You Find Newport Beach Liposuction center?

    Finding the clinic that performs liposuctions in Newport Beach is... Read More

    5 Easy Steps to Help You Lose Weight

    When losing weight, most of us don't have the time... Read More

    How to Lose Weight: Food for Thought

    When it comes to weight loss, most of us would... Read More

    Lose Weight the Healthy Way

    It's definitely no fun to lose weight -- put it... Read More

    Rapid Weight Loss Tips, Techniques and Strategies

    It seems everyone is looking for that magic bullet -... Read More

    Fat Burning Foods

    Are there any foods that burn body fat? If yes,... Read More

    The #1 Key to Weight Loss ? What You DON?T Want to Know and Most Won?t Tell You!

    You may not like what I have to say, even... Read More

    Were Cave Dwellers Ever Fat?

    In our mind's eye, we see our ancient ancestors as... Read More

    Will I get faster results with a Personal Trainer?

    If you pick the right personal trainer?you'll most definitely see... Read More

    Dieters : Put MORE Focus on Food

    If you're always on a diet you probably spend half... Read More

    The Secret To Permanent Weight Loss

    AND SAVE MONEY IN THE PROCESS. The secret is simple... Read More

    induction street high bay led lighting fixtures Pete's produce ..
    induction street high bay led lighting fixtures Pete's produce ..